Acetone is the organic compound with the formula (CH3)2CO. This colorless, mobile, flammable liquid is the simplest example of the ketones. Acetone is miscible with water and serves as an important solvent in its own right, typically as the solvent of choice for cleaning purposes in the laboratory. About 5.1 million tonnes were produced worldwide in 2009, mainly for use as a solvent and production of methyl methacrylate and bisphenol A. Familiar household uses of acetone are as the active ingredient in nail polish remover and as paint thinner. It is a common building block in organic chemistry.
Acetone is either slightly irritating or not irritating, based on animal and limited human information. Application of 1 mL of acetone in a small glass tube to six male volunteers for 30 or 90 minutes resulted in only mild redness and swelling at 90 minutes.
The risk of developing health effects following the absorption of acetone through unbroken skin is very slight. There are several reports of people, usually young children, becoming ill following skin exposure to acetone while lightweight casts were being put on broken limbs. The symptoms experienced were similar to those described following high inhalation exposures. In all cases, a large amount of acetone came into contact with the skin for several hours and inhalation exposure may also have occurred. These reports are not considered relevant to people exposed to acetone at work.
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